Vulcanolide is a highly potent synthetic fragrance agent belonging to the polycyclic musk family. Primarily developed and patented within the flavor and fragrance industry, Vulcanolide is celebrated for its unique structural features and exceptional olfactive performance .Vulcanolide's chemical characteristics are tied to its specific stereochemical structure, which governs its interactions with human olfactory receptors.

Appearance: a clear colorless to pale yellow viscous liquid or crystalline mass at room temperature.

Purty(GC): >96%

Fragrance and Olfactory Profile

Musks act as crucial fixatives, lending substantive volume, longevity, and warmth to a composition.

Odor Type: Powerful, sophisticated polycyclic musk.

Odor Description: It delivers a clean, earthy, yet radiant musk profile with subtle woody and warm facets. Unlike older generations of nitro-musks, Vulcanolide offers a highly vibrant, diffusive quality that elevates both the top notes and base notes of a fragrance configuration.

Threshold: It possesses a remarkably low odor detection threshold, meaning a exceptionally small amount is required to achieve a perceptible and lasting impact in a formulation

Based on its molecular architecture and classification as a perfumery aldehyde intermediate, the material is understood to function as a specialty fragrance ingredient intended for fine fragrance and functional fragrance compositions. However, verified public-domain odor descriptors for this exact CAS number are scarce, and unsupported sensory claims should therefore be avoided.

Polycyclic aldehydes of this type are generally valued in perfumery because they may contribute:

High substantivity

Excellent diffusion characteristics

Stability in complex formulations

Long-lasting performance on substrates

Because stereochemistry significantly affects odor behavior in fragrance chemistry, the defined chiral configuration ((6S,7S)) is likely important to its olfactory profile and commercial value.

Industrial Applications

Vulcanolide is utilized almost exclusively within the Fine Fragrance and Functional Perfumery sectors:

Fine Perfumery: It serves as a structural core or modifier in luxury perfumes and colognes. Its strong fixative properties slow down the evaporation rate of more volatile ingredients, ensuring the perfume's character remains consistent over time.

Consumer Products: Due to its chemical stability, it is incorporated into premium personal care products (cosmetics, body washes, and lotions) and fabric care formulations (laundry detergents and softeners) where long-lasting "freshness" and substantivity on fabric are heavily required (Synthetic musk odorants in cosmetic products, n.d.).

Academic and Computational Research: Beyond consumer goods, Vulcanolide's rigid lipophilic structure has drawn modern interest in computational biology and molecular docking studies. For instance, in silico screenings evaluating hydrophobic compounds have occasionally explored its structural stability and binding affinities within viral protease models.

Due to its stereochemically defined structure, the material is relevant in:

• Chiral fragrance chemistry
• Structure–odor relationship studies
• Synthetic aroma chemical development
• High-performance fragrance ingredient screening

Safety and Regulatory Considerations

As with many aldehydic fragrance materials, standard industrial handling precautions are recommended:

Avoid direct inhalation

Prevent prolonged skin exposure

Use appropriate ventilation

Store in tightly sealed containers away from oxidation sources

Product:167254-80-0,Vulcanolide,Fragrance,Perfume ingredient